Could a simple supplement make chemo work better for advanced colon cancer?
NCT ID NCT06509880
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This trial investigates whether adding a dietary supplement called sodium nucleinate to standard FOLFOX chemotherapy helps people with metastatic colorectal cancer (cancer that has spread). Participants are randomly assigned to receive either the supplement or a placebo alongside four cycles of chemotherapy. Researchers track treatment completion, quality of life, and survival up to one year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
sodium nucleinate (Adenorine)
What this could lead to
If it works, this could point toward a way to make chemotherapy more effective and improve daily life for people with advanced colorectal cancer.
What could go wrong
This is a mid-stage trial with 187 participants, so results may not apply to everyone. The supplement may not provide added benefit and could cause unexpected side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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MIPOClinic
Almaty, Almaty, 050038, Kazakhstan