Could a simple supplement make chemo work better for advanced colon cancer?

NCT ID NCT06509880

Completed Disease control Sponsor: MIPO Clinic Source: ClinicalTrials.gov ↗

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This trial investigates whether adding a dietary supplement called sodium nucleinate to standard FOLFOX chemotherapy helps people with metastatic colorectal cancer (cancer that has spread). Participants are randomly assigned to receive either the supplement or a placebo alongside four cycles of chemotherapy. Researchers track treatment completion, quality of life, and survival up to one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sodium nucleinate (Adenorine)
What this could lead to: If it works, this could point toward a way to make chemotherapy more effective and improve daily life for people with advanced colorectal cancer.
What could go wrong: This is a mid-stage trial with 187 participants, so results may not apply to everyone. The supplement may not provide added benefit and could cause unexpected side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MONITORING, IMMUNOLOGIC

Contacts and locations

Locations

MIPOClinic

Almaty, Almaty, 050038, Kazakhstan

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