Scientists uncover how a drug fights smell loss in sinus sufferers

NCT ID NCT05964465

First seen Mar 08, 2026 · Last updated May 16, 2026 · Updated 7 times

Summary

This study looked at how dupilumab improves smell in people with chronic sinusitis and nasal polyps. Researchers measured changes in inflammation inside the nose using CT scans, endoscopy, and mucus samples. The goal was to confirm that the drug works by directly reducing swelling in the smell region. 60 adults who were already planning to take dupilumab took part.

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Contacts and locations

Locations

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • University of Virginia

    Charlottesville, Virginia, 22904, United States

Conditions

Explore the condition pages connected to this study.