Could a breathing app and exercise team up to beat high blood pressure?
NCT ID NCT07717996
First seen Jul 21, 2026 · Last updated Jul 23, 2026 · Updated 2 times
Summary
This study looks at whether using a smartphone app to guide slow breathing, combined with aerobic exercise, can help lower blood pressure in people with essential hypertension. Seventy-five adults aged 40-50 with stage 1-2 hypertension will be split into three groups: breathing plus exercise, exercise alone, or breathing alone, all for 12 weeks. The main goal is to see if the combination works better than either approach alone for improving blood pressure, heart health, and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- smartphone-guided paced breathing and aerobic exercise
- What this could lead to
- If it works, this could offer a simple, low-cost, drug-free way to help control blood pressure and improve daily life for people with hypertension.
- What could go wrong
- This is a small, early-stage trial with only 75 participants, so results may not apply to everyone. The benefits may be modest or no better than standard care.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 75 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Adults aged 40-50 years. Both males and females. Clinically diagnosed with essential (primary) hypertension confirmed by a physician. Stage 1-2 hypertension (SBP 130-160 mmHg and/or DBP 80-100 mmHg) based on standardized clinical measurement. Duration of diagnosed hypertension between 6 months and 5 years. Stable on antihypertensive medication for at least 4 weeks prior to enrollment, with no planned medication changes. Medically stable and cleared for participation in moderate-intensity exercise. Able to understand instructions and independently perform smartphone-guided breathing exercises. Willing to participate and provide written informed consent. Exclusion Criteria: Secondary hypertension (e.g., renal, endocrine, or medication-induced hypertension). Severe or uncontrolled hypertension (SBP \>180 mmHg and/or DBP \>110 mmHg). History of major cardiovascular events (e.g., myocardial infarction within the past 6 months, unstable angina, uncontrolled arrhythmias, or decompensated heart failure). Chronic respiratory diseases affecting exercise tolerance (e.g., chronic obstructive pulmonary disease \[COPD\] or severe asthma). Neurological, musculoskeletal, or orthopedic conditions that limit safe participation in walking or exercise training. Cognitive impairment or psychiatric disorders that affect comprehension or adherence to the study protocol. Participation in a structured exercise or pulmonary rehabilitation program within the previous 3 months. Heavy smoking. Pregnancy or lactation. Contraindications to exercise testing or training according to the American College of Sports Medicine (ACSM) guidelines. Anticipated changes in antihypertensive medication during the study period.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
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