Scientists peek inside muscles of kids with SMA to see how drugs really work

NCT ID NCT06532474

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 27 times

Summary

This study watches how spinal muscular atrophy (SMA) drugs change muscles and nerves in 24 children aged 5 to 20. Using MRI scans, strength tests, and blood samples, researchers track changes over a year. The goal is not to test a new treatment but to better understand how existing therapies affect the body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St. Jude Children's Research Hospital

    RECRUITING

    Memphis, Tennessee, 38105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

spinal muscular atrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.