Can a new infusion drug tame advanced solid tumors?
NCT ID NCT06087770
First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This early-phase trial is testing an experimental drug called SM3321 in people with advanced solid tumors that have stopped responding to standard treatments. The main goal is to see if the drug is safe and tolerable, and to find the best dose. Participants receive SM3321 as a weekly intravenous infusion over 28-day cycles.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- an experimental drug called SM3321 given by intravenous infusion once a week
- What this could lead to
- If safe and effective, SM3321 could offer a new treatment option for people with advanced solid tumors who have run out of standard therapies.
- What could go wrong
- This is an early, small phase 1 trial focused on safety, not yet on how well the drug works. The drug may cause side effects or fail to shrink tumors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Shanghai General Hospital
Shanghai, Shanghai Municipality, 201210, China
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Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Guangzhou, Guangdong, 510120, China
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The second affiliated hospital Zhejiang university School of Medicine
Hangzhou, Zhejiang, 310009, China
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