New Two-Drug combo tested to shrink tough tumors
NCT ID NCT06036836
Summary
This study tested a new combination drug (MK-4280A) to see if it could help people with certain advanced cancers. It involved 163 people with either a type of advanced skin cancer (cSCC) or a type of endometrial cancer that had spread or returned. The goal was to see if the drug could shrink or eliminate tumors before surgery for the skin cancer group, or control the disease for the endometrial cancer group.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Ankara Bilkent Şehir Hastanesi ( Site 0427)
Ankara, 06800, Turkey (Türkiye)
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Blacktown Hospital ( Site 0003)
Sydney, New South Wales, 2148, Australia
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CENTRE LEON BERARD ( Site 0151)
Lyon Cedex08, Auvergne-Rhône-Alpes, 69373, France
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Centre Hospitalier Régional Universitaire de Brest - Hôpital Morvan ( Site 0154)
Brest, Finistere, 29200, France
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Centre Hospitalier de l'Université de Montréal ( Site 0602)
Montreal, Quebec, H2X 3E4, Canada
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Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 0
Québec, Quebec, G1J 1Z4, Canada
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Cleveland Clinic Main ( Site 0639)
Cleveland, Ohio, 44195, United States
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Dana-Farber Cancer Institute ( Site 0642)
Boston, Massachusetts, 02215, United States
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Duke Cancer Institute ( Site 0641)
Durham, North Carolina, 27710, United States
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Erasmus Medisch Centrum ( Site 0272)
Rotterdam, South Holland, 3015 GD, Netherlands
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Fiona Stanley Hospital ( Site 0006)
Murdock, Western Australia, 6150, Australia
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Fondazione IRCCS Istituto Nazionale dei Tumori-SC Oncologia Medica 3 - Tumori Testa-collo ( Site 025
Milan, Lombardy, 20133, Italy
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Gulhane Egitim Arastirma Hastanesi-Onkoloji ( Site 0424)
Ankara, 06010, Turkey (Türkiye)
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Hacettepe Universite Hastaneleri-oncology hospital ( Site 0421)
Ankara, 06230, Turkey (Türkiye)
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Hopitaux Universitaires Paris Centre-Hopital Cochin ( Site 0155)
Paris, 75014, France
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Hospital Sultan Ismail-Pusat Rawatan Radioterapi Dan Onkologi ( Site 0063)
Johor Bahru, Johor, 81100, Malaysia
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Institut de cancérologie Strasbourg Europe (ICANS) ( Site 0153)
Strasbourg, Alsace, 67200, France
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Istituto Nazionale Tumori IRCCS Fondazione Pascale-s.c. melanoma, immunoterapia oncologica e terapi
Naples, 80131, Italy
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Jewish General Hospital ( Site 0605)
Montreal, Quebec, H3T 1E2, Canada
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Liv Hospital Ankara-Oncology ( Site 0426)
Ankara, 06680, Turkey (Türkiye)
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McGill University Health Centre ( Site 0604)
Montreal, Quebec, H4A 3J1, Canada
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Medipol Mega Universite Hastanesi-oncology ( Site 0425)
Stanbul, Istanbul, 34214, Turkey (Türkiye)
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National Cheng Kung University Hospital-Clinical Trial Center ( Site 0032)
Tainan, 704, Taiwan
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National Taiwan University Hospital ( Site 0031)
Taipei, 10002, Taiwan
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Princess Margaret Cancer Centre ( Site 0606)
Toronto, Ontario, M5G 2M9, Canada
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Radboudumc ( Site 0274)
Nijmegen, Gelderland, 6525 GA, Netherlands
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Royal Brisbane and Women's Hospital ( Site 0002)
Brisbane, Queensland, 4029, Australia
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Royal North Shore Hospital ( Site 0008)
St Leonards, New South Wales, 2065, Australia
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Rutgers Cancer Institute of New Jersey ( Site 0635)
New Brunswick, New Jersey, 08903, United States
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Sarawak General Hospital-Radiotherapy Unit ( Site 0062)
Kuching, Sarawak, 93586, Malaysia
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St Vincent's Hospital-The Kinghorn Cancer Centre ( Site 0005)
Darlinghurst, New South Wales, 2010, Australia
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St. Luke's University Health Network ( Site 0636)
Bethlehem, Pennsylvania, 18015, United States
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Sunnybrook Research Institute ( Site 0607)
Toronto, Ontario, M4N 3M5, Canada
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TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 0423)
Istanbul, 34722, Turkey (Türkiye)
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Taichung Veterans General Hospital-GYNECOLOGY ( Site 0033)
Taichung, 407, Taiwan
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The Alfred Hospital ( Site 0004)
Melbourne, Victoria, 3004, Australia
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UPMC Hillman Cancer Center ( Site 0644)
Pittsburgh, Pennsylvania, 15232, United States
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UT Southwestern Medical Center-CRO-Simmons Comprehensive Cancer Center ( Site 0645)
Dallas, Texas, 75390-9179, United States
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Universitaetsklinikum Carl Gustav Carus Dresden-Klinik und Poliklinik für Dermatologie ( Site 0183)
Dresden, Saxony, 01307, Germany
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Universitaetsklinikum Essen ( Site 0185)
Essen, North Rhine-Westphalia, 45147, Germany
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Universitaetsklinikum Essen-Klinik für Dermatologie, Venerologie und Allergologie ( Site 0182)
Essen, North Rhine-Westphalia, 45147, Germany
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University Malaya Medical Centre ( Site 0061)
Lembah Pantai, Kuala Lumpur, 59100, Malaysia
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University Medical Center Groningen ( Site 0273)
Groningen, 9713GZ, Netherlands
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Yale-New Haven Hospital-Yale Cancer Center ( Site 0643)
New Haven, Connecticut, 06510, United States
Conditions
Explore the condition pages connected to this study.