Skin gel shows promise in blocking cancer before it starts

NCT ID NCT02636569

First seen Jan 22, 2026 · Last updated May 15, 2026 · Updated 14 times

Summary

This study tested whether a topical gel containing diclofenac can reverse certain biomarkers linked to non-melanoma skin cancer, potentially preventing the disease. Twenty-four adults at high risk applied the gel once or twice daily, and researchers measured changes in skin biomarkers and actinic keratoses (precancerous spots). The goal was to find the best dose for reducing cancer risk.

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Contacts and locations

Locations

  • University of Alabama at Birmingham Whitaker Clinic

    Birmingham, Alabama, 35233, United States

Conditions

Explore the condition pages connected to this study.