New cancer drug SKB571 enters first human tests

NCT ID NCT06725381

Recruiting now Disease control Sponsor: Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests a new drug called SKB571 in 138 adults with advanced solid tumors that have spread or cannot be removed by surgery. The main goal is to check safety and find the right dose, while also looking for signs that the drug shrinks tumors. Participants receive SKB571 every three weeks until their disease gets worse or side effects become too severe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: SKB571
What this could lead to: If it works, this could point toward a new treatment option for people with advanced solid tumors that have not responded to other therapies.
What could go wrong: This is a very early, first-in-human trial with only 138 participants, so safety and effectiveness are not yet proven. Many early-stage cancer drugs do not advance to later trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOLID MALIGNANCIES

Contacts and locations

Locations

Bei Jing Cancer Hospital
NOT_YET_RECRUITING

Beijing, China
Chongqing University Cancer Hospital
RECRUITING

Chongqing, China
Guangxi Medical University Cancer Hospital
RECRUITING

Nanning, Guangxi, China
Guangxi Medical University Cancer Hospital
RECRUITING

Linyi, Shandong, China
Hubei Cancer Hospital
RECRUITING

Wuhan, Hubei, China
Hunan Cancer Hospital
RECRUITING

Changsha, Hunan, China
Shandong Cancer Hospital
RECRUITING

Jinan, Shandong, China
Shanghai East Hospital
RECRUITING

Shanghai, China
Shanghai Pulmonary Hospital
NOT_YET_RECRUITING

Shanghai, China
Si Chuan Cancer Hospital
RECRUITING

Chengdu, Sichuan, China
Sun Yat-sen University Cancer Center
RECRUITING

Guangzhou, Guangdong, China
The Affliated Hospital of Nanjing University Medical School
RECRUITING

Nanjing, Jiangsu, China
West China Hospital, Sichuan University
RECRUITING

Chengdu, Sichuan, China
Zhejiang Cancer Hospital
RECRUITING

Hangzhou, Zhejiang, China
Zhongshan Hospital
RECRUITING

Shanghai, China

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