New eye drops aim to soothe Sjögren's dry eye
NCT ID NCT07118241
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a protein-based eye drop (rhPRG4) can safely relieve dry eye symptoms in people with Sjögren's syndrome. About 80 adults will receive either the active drops or a placebo for 28 days. The main goal is to see if the drops can clear corneal staining, a sign of eye surface damage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
recombinant human proteoglycan 4 (rhPRG4) eye drops
What this could lead to
If it works, this could lead to a new treatment option for dry eye in people with Sjögren's syndrome, potentially improving comfort and eye health.
What could go wrong
This is a small Phase 2 trial with only 80 people, so results may not apply to everyone. The treatment may not work better than a placebo, and side effects are still being studied.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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OTA
RECRUITINGBrisbane, Queensland, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Queensland University of Technology
RECRUITINGBrisbane, Queensland, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sydney Eye Hospital
NOT_YET_RECRUITINGSydney, New South Wales, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Univ of New South Wales
RECRUITINGSydney, New South Wales, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Melbourne
RECRUITINGMelbourne, Victoria, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of the Sunshine Coast
RECRUITINGMaroochydore, Queensland, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••