New urine test may spare bladder cancer patients from overtreatment

NCT ID NCT07252297

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at whether a test that checks for a specific gene marker (SIX6) in urine or tissue can predict if bladder cancer will come back after surgery. Researchers will compare SIX6 levels in 177 patients who had low-risk bladder cancer to see if the test can tell who is likely to have a recurrence. If it works, doctors could use this test to avoid giving extra treatments to patients who don't need them.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SIX6 Gene Methylation Assay

What this could lead to

If successful, this test could help doctors better predict which bladder cancer patients are at risk of recurrence, allowing for more personalized treatment and fewer unnecessary therapies.

What could go wrong

This is a small, retrospective study, so results may not apply to all patients. The test is still experimental and needs larger trials to confirm its accuracy and usefulness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

disease non-invasive bladder urothelial carcinoma Non-Muscle Invasive Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Xi Jing Hopspital

    Xi'an, ShannxI, 710300, China