Could a 3-Day drug infusion shield organs after aortic tear surgery?

NCT ID NCT07156656

First seen Sep 30, 2025 · Last updated May 13, 2026 · Updated 28 times

Summary

This study tests whether a drug called sivelestat sodium can protect organ function in people who have surgery for a life-threatening tear in the main artery from the heart (type A aortic dissection). About 236 adults will receive either the drug or a placebo through a vein for 3 days after surgery. Researchers will measure organ health scores and recovery over the first 5 days and track outcomes for 28 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Changhai Hospital of Shanghai

    Shanghai, Shanghai Municipality, China

    Contact Phone: •••-•••-••••

  • Fujian Provincial Hospital

    Fuzhou, Fujian, China

    Contact Phone: •••-•••-••••

  • Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences) (Guangdong Provincial People's Hospital Affiliated to Southern Medical University)

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-••••

  • The First Affiliated Hospital of Anhui Medical University

    Hefei, Anhui, China

    Contact Phone: •••-•••-••••

  • The First Affiliated Hospital of Xi'an Jiao Tong University

    Xi'an, Shaanxi, China

    Contact Phone: •••-•••-••••

  • The University of Hong Kong - Shenzhen Hospital

    Shenzhen, Guangdong, China

    Contact Phone: •••-•••-••••

Conditions

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