New combo therapy shows promise for untreatable liver cancer

NCT ID NCT07610551

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a combination of three treatments—radioactive beads (SIRT-Y90), an immunotherapy drug (atezolizumab), and a drug that cuts off tumor blood supply (bevacizumab)—for people with advanced liver cancer that cannot be surgically removed. Researchers will track how well the tumors shrink and how long patients live, using data from about 50 participants across eight hospitals in China. The goal is to see if this triple approach is safe and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
SIRT-Y90 (radioactive beads), atezolizumab (immunotherapy), bevacizumab (anti-angiogenic drug)
What this could lead to
If successful, this combination could offer a new treatment option for people with advanced liver cancer that cannot be removed by surgery, potentially shrinking tumors and extending life.
What could go wrong
This is a small, early-stage study with only 50 participants, so results may not apply to everyone. Combining these treatments may also increase side effects like liver damage or bleeding.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • No. 777, Xitai Road, Chang'an District, Xi'an City, Shaanxi Province, China

    RECRUITING

    Xi’an, Shanxi, 710000, China

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