Immunotherapy before standard treatment may boost survival in esophageal cancer

NCT ID NCT07306663

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This phase 3 trial tests whether adding immunotherapy (sintilimab) and chemotherapy before standard chemoradiotherapy helps people with inoperable esophageal cancer live longer and reduces the chance of the cancer coming back. About 242 adults aged 18-75 with stage 2-4 esophageal cancer will be randomly assigned to receive either the new combination or standard treatment alone. The study tracks survival, side effects, and how well the cancer responds.

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Conditions

The condition(s) this trial relates to.

esophageal cancer Esophageal Neoplasms esophageal squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Jiangsu Cancer Hospital

    Nanjing, Jiangsu, 210009, China