Immunotherapy before standard treatment may boost survival in esophageal cancer

NCT ID NCT07306663

First seen Jan 08, 2026 · Last updated Apr 26, 2026 · Updated 20 times

Summary

This phase 3 trial tests whether adding immunotherapy (sintilimab) and chemotherapy before standard chemoradiotherapy helps people with inoperable esophageal cancer live longer and reduces the chance of the cancer coming back. About 242 adults aged 18-75 with stage II-IVA esophageal cancer will either receive the new combination or standard treatment alone. Researchers will track survival, side effects, and tumor response.

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Contacts and locations

Locations

  • Jiangsu Cancer Hospital

    Nanjing, Jiangsu, 210009, China

Conditions

Explore the condition pages connected to this study.