Cholesterol drug may boost cancer therapy in genetic subtype

NCT ID NCT07213557

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 31 times

Summary

This study tests whether adding simvastatin, a common cholesterol medication, to standard chemotherapy and immunotherapy can help people with a specific genetic type of advanced stomach or esophagus cancer. About 84 adults whose cancer has a mutation in the ARID1A gene will receive either the standard treatment plus simvastatin or standard treatment alone. The goal is to see if the combination slows cancer growth longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Istituto Nazionale Tumori Fondazione G. Pascale

    RECRUITING

    Naples, Italia, 80131, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.