One shot or several? new study tests best radiation dose for spreading cancer

NCT ID NCT05784428

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 30 times

Summary

This study compares giving a single high-dose radiation treatment versus several smaller doses for people whose cancer has spread to a few places (up to 5 spots). The goal is to see which approach causes fewer side effects, better controls the cancer, and improves quality of life. About 598 adults with stable or slowly growing cancer will take part, and some will also use a symptom-tracking app to help manage side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • BC Cancer

    RECRUITING

    Kelowna, British Columbia, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • BC Cancer

    RECRUITING

    Prince George, British Columbia, V2M 7E9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • BC Cancer

    RECRUITING

    Surrey, British Columbia, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • BC Cancer

    RECRUITING

    Vancouver, British Columbia, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • BC Cancer - Victoria

    NOT_YET_RECRUITING

    Victoria, British Columbia, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Beacon Hospital

    RECRUITING

    Dublin, Leinster, D18 AK68, Ireland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Bon Secours Radiotherapy Cork in Partnership with UPMC Hillman Cancer Centre

    RECRUITING

    Cork, Munster, T12 DV56, Ireland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cork University Hospital

    RECRUITING

    Cork, Munster, T12 DC4A, Ireland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mater Private Hospital

    RECRUITING

    Dublin, Leinster, D07 WKW8, Ireland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Princess Margaret Cancer Centre | University Health Network

    RECRUITING

    Toronto, Ontario, M5G 1X6, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Luke's Radiation Oncology Network

    RECRUITING

    Dublin, Dublin, D06 E1C9, Ireland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UPMC Whitfield Hospital - Waterford

    RECRUITING

    Waterford, Munster, X91 DH9W, Ireland

    Contact

    Contact Email: •••••@•••••

  • University Hospital Galway

    RECRUITING

    Galway, Connacht, H91 YR71, Ireland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.