Simple drugs may make a tricky gut procedure smoother
NCT ID NCT07461389
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tested whether giving simethicone (a defoaming agent) and dicyclomine (which reduces gut spasms) before or during an ERCP procedure improves how well doctors can see and work. 90 adults were split into three groups: one got no extra medication, one got simethicone before the procedure, and one got it during. The goal was to see if these drugs led to clearer views and less gut movement, making the procedure quicker and easier for the doctor.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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90 people
The number who actually took part.
- Started
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Oct 2025
- Finished
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Apr 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. All patients presenting for ERCP older than 18years of age. 2. Patients willing to participate in the study, meeting criteria No. 1 Exclusion Criteria: 1. Cases that are abandoned due to inability to access the ampulla 2. Patients with grossly altered anatomy resulting in extended procedure time
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CMH Lahore Medical College
Lahore, Punjab Province, Pakistan