New Triple-Targeting antibody enters human testing for Tough-to-Treat blood cancer
NCT ID NCT06375044
Summary
This early-stage trial is testing a new experimental antibody called SIM0500 in adults with advanced multiple myeloma that has returned or stopped responding to all standard treatments. The study aims to find a safe dose and see if the treatment shows early signs of fighting the cancer. About 130 participants will receive the treatment until their cancer worsens, side effects become too severe, or they choose to leave the study.
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Contacts and locations
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Study contacts
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Contact
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Locations
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Beijing Chaoyang Hospital Capital Medical University
RECRUITINGBeijing, Beijing Municipality, 100000, China
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Dana Farber Cancer institution
NOT_YET_RECRUITINGBoston, Massachusetts, 02215, United States
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Henan Cancer Hospital
RECRUITINGZhengzhou, Henan, 450000, China
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Icahn School of Medicine at Mount Sinai，The Tisch Cancer Institute
RECRUITINGNew York, New York, 10029, United States
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Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences
RECRUITINGTianjin, Tianjin Municipality, 300000, China
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Laura & Isaac Perlmutter Cancer Center at NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
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Mayo Clinic Arizona
RECRUITINGPhoenix, Arizona, 85054, United States
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Mayo Clinic Florida
RECRUITINGJacksonville, Florida, 32224, United States
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Mayo Clinic Rochester
RECRUITINGRochester, Minnesota, 55905, United States
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Sun Yat-sen University Cancer Center
RECRUITINGGuangzhou, Guangdong, 510000, China
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The First Affiliated Hospital Zhejiang University School of Medicine
RECRUITINGHanzhou, Zhejiang, 310000, China
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Conditions
Explore the condition pages connected to this study.