Can a common heart drug help fragile preemies? new study tests safety

NCT ID NCT04447989

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at whether the drug sildenafil is safe for premature infants with a severe lung condition called bronchopulmonary dysplasia (BPD). The study included 125 babies in hospital intensive care units. Researchers monitored for dangerously low blood pressure as the main safety measure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bronchopulmonary dysplasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Arkansas Children's Research Institute

    Little Rock, Arkansas, 72202, United States

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

  • Children's Hospital of Nevada at University Medical Center

    Las Vegas, Nevada, 89102, United States

  • Childrens Mercy Hospital

    Kansas City, Missouri, 64108, United States

  • Childrens National Medical Center

    Washington D.C., District of Columbia, 20010, United States

  • East Carolina University

    Greenville, North Carolina, 27858, United States

  • Emory Children's Center

    Atlanta, Georgia, 30322, United States

  • Lurie Children's Hospital

    Chicago, Illinois, 60611-2605, United States

  • Ochsner Baptist Medical Center

    New Orleans, Louisiana, 70115, United States

  • Rady Children's Hospital and Health Center

    San Diego, California, 92123, United States

  • Rainbow Babies and Childrens Hospital

    Cleveland, Ohio, 44106, United States

  • University of Arkansas Medical Sciences

    Little Rock, Arkansas, 72205, United States

  • University of Florida Jacksonville Shands Medical Center

    Jacksonville, Florida, 32209, United States

  • University of Illinois at Chicago

    Chicago, Illinois, 60611, United States

  • University of Kentucky Chandler Medical Center

    Lexington, Kentucky, 40506, United States

  • University of Louisville School of Medicine

    Louisville, Kentucky, 40202, United States

  • University of Mississippi Medical Center

    Jackson, Mississippi, 39216, United States

  • University of NC at Chapel Hill

    Chapel Hill, North Carolina, 27599, United States

  • University of Rochester School of Medicine Children's Hospital

    Rochester, New York, 14642, United States

  • University of Tennessee Health Science Center

    Memphis, Tennessee, 38163, United States

  • University of Texas Health

    Austin, Texas, 78723, United States

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27157, United States

  • Westchester Medical Center - New York Medical College

    Valhalla, New York, 10595, United States

  • Wolfson Children's Hospital

    Jacksonville, Florida, 32209, United States

  • Women's Hospital of Texas

    Houston, Texas, 77054, United States