New drug aimed at making risky sickle cell transplants safer

NCT ID NCT06078696

Summary

This study tested whether adding a drug called siplizumab to a stem cell transplant could make the procedure safer and more effective for adults with severe sickle cell disease. The main goal was to see if the drug could prevent the donor cells from being rejected (graft failure) and reduce a dangerous complication where donor cells attack the patient's body. The study was stopped early after enrolling only one participant.

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Contacts and locations

Locations

  • Columbia University Irving Medical Center

    New York, New York, 10032, United States

Conditions

Explore the condition pages connected to this study.