New radiation method aims to make stem cell transplants safer for sickle cell patients
NCT ID NCT05384756
First seen Jan 07, 2026 · Last updated May 14, 2026 · Updated 24 times
Summary
This early-phase trial tests a new way to prepare the body for a stem cell transplant in people with sickle cell disease. Instead of full-body radiation, doctors use targeted radiation to the bone marrow and lymph nodes along with a drug called alemtuzumab. The goal is to reduce damage to healthy organs and lower the risk of graft-versus-host disease. Only 2 participants were enrolled to check safety and feasibility.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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City of Hope Medical Center
Duarte, California, 91010, United States
Conditions
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