First human test of sickle cell pill halted early

NCT ID NCT05660265

Summary

This was a very early, first-in-human study to check if a new oral drug called GSK4172239D was safe and how it moved through the body in people with sickle cell disease. Only 11 participants received a single dose of either the drug or a placebo. The study was terminated early, and its main goal was to gather initial safety data, not to treat the disease.

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Contacts and locations

Locations

  • GSK Investigational Site

    Miami, Florida, 33155, United States

  • GSK Investigational Site

    Tamarac, Florida, 33321, United States

  • GSK Investigational Site

    Atlanta, Georgia, 30315, United States

  • GSK Investigational Site

    Columbus, Georgia, 31904, United States

  • GSK Investigational Site

    Riverdale, Georgia, 30274, United States

  • GSK Investigational Site

    Las Vegas, Nevada, 89113, United States

Conditions

Explore the condition pages connected to this study.