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Sharper radiation beam aims to hit High-Risk prostate cancer harder, spare healthy tissue

NCT ID NCT07693075

Recruiting now Disease control Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This trial tests a specialized radiation technique called SIB-VMAT for men with high-risk or very high-risk localized prostate cancer. The approach delivers a higher radiation dose to the tumor while giving a standard dose to nearby lymph nodes, all in 20 sessions over four weeks. Researchers are evaluating whether this method reduces side effects and improves early cancer control compared to standard radiotherapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Simultaneous Integrated Boost Volumetric Modulated Arc Therapy (SIB-VMAT)
What this could lead to
If successful, this approach could offer a more effective and safer radiotherapy option for men with high-risk prostate cancer, potentially improving cancer control and quality of life.
What could go wrong
This is a small, early-phase study (30 participants) focused on safety and early signs of effectiveness. The technique may not prove superior to standard radiotherapy, and side effects remain a possibility.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER PATIENTS TREATED BY RADIOTHERAPY

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Faculty of Medicine - Menoufia University

    RECRUITING

    Shibīn al Kawm, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Faculty of Medicine - Sohag University

    RECRUITING

    Sohag, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Faculty of Medicine, Ain Shams University

    RECRUITING

    Cairo, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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