New targeted therapy aims to extend life in stomach cancer
NCT ID NCT06649292
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 3 trial tests a new drug, SHR-A1904, in 524 people with advanced stomach or gastroesophageal junction cancer that has a specific protein (CLDN18.2). Participants receive either SHR-A1904 or standard chemotherapy. The main goal is to see if the new drug helps people live longer. The study is currently recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
SHR-A1904 (an antibody-drug conjugate targeting CLDN18.2)
What this could lead to
If successful, this could provide a new targeted treatment option for people with advanced gastric cancer whose tumors have a specific marker (CLDN18.2).
What could go wrong
This is a Phase 3 trial, but the drug is still experimental. It may not improve survival compared to current chemotherapies, and side effects from the targeted therapy could be significant.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sun Yat-sen University Cancer Center
RECRUITINGGuangzhou, Guangdong, 510060, China
Contact