New heart failure drug candidate enters first human safety trial

NCT ID NCT07230145

First seen Nov 17, 2025 · Last updated May 13, 2026 · Updated 25 times

Summary

This early-stage study tests a single injection of SHR-4658 in 48 healthy people and those with high blood pressure to see if it is safe and how the body handles it. The goal is to gather initial safety data for a potential heart failure treatment. Participants must be 18-55 and meet specific blood pressure and weight criteria.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Anzhen Hospital Capital Medical University

    Beijing, Beijing Municipality, 100029, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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