Shorter radiation course tested to control prostate cancer with fewer side effects

NCT ID NCT03274687

Completed Disease control Sponsor: NRG Oncology Source: ClinicalTrials.gov ↗

Summary

This study tested if a shorter, more intense radiation schedule (5 weeks) works as well as the standard longer schedule (7 weeks) for men who had surgery for prostate cancer. The main goal was to see if the shorter treatment caused fewer bowel and urinary side effects while still controlling the cancer. Nearly 300 men participated in this completed Phase 3 trial.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Adena Regional Medical Center

Chillicothe, Ohio, 45601, United States
Allan Blair Cancer Centre

Regina, Saskatchewan, S4T 7T1, Canada
American Fork Hospital / Huntsman Intermountain Cancer Center

American Fork, Utah, 84003, United States
Arnot Ogden Medical Center/Falck Cancer Center

Elmira, New York, 14905, United States
Arthur J E Child Comprehensive Cancer Centre

Calgary, Alberta, T2N 5G2, Canada
Ascension All Saints Hospital

Racine, Wisconsin, 53405, United States
Ascension Mercy Hospital

Oshkosh, Wisconsin, 54904, United States
Ascension Saint Elizabeth Hospital

Appleton, Wisconsin, 54915, United States
Ascension Saint Francis - Reiman Cancer Center

Franklin, Wisconsin, 53132, United States
Ascension Southeast Wisconsin Hospital - Elmbrook Campus

Brookfield, Wisconsin, 53045, United States
Ascension Via Christi Hospitals Wichita

Wichita, Kansas, 67214, United States
Aspirus Cancer Care - Wisconsin Rapids

Wisconsin Rapids, Wisconsin, 54494, United States
Augusta Health Center for Cancer and Blood Disorders

Fishersville, Virginia, 22939, United States
Aurora Bay Area Medical Group-Marinette

Marinette, Wisconsin, 54143, United States
Aurora BayCare Medical Center

Green Bay, Wisconsin, 54311, United States
Aurora Cancer Care-Grafton

Grafton, Wisconsin, 53024, United States
Aurora Cancer Care-Kenosha South

Kenosha, Wisconsin, 53142, United States
Aurora Medical Center in Summit

Summit, Wisconsin, 53066, United States
Aurora Saint Luke's Medical Center

Milwaukee, Wisconsin, 53215, United States
Aurora Sinai Medical Center

Milwaukee, Wisconsin, 53233, United States
Aurora West Allis Medical Center

West Allis, Wisconsin, 53227, United States
Beebe Health Campus

Rehoboth Beach, Delaware, 19971, United States
Benefis Sletten Cancer Institute

Great Falls, Montana, 59405, United States
Beth Israel Deaconess Hospital-Plymouth

Plymouth, Massachusetts, 02360, United States
Billings Clinic Cancer Center

Billings, Montana, 59101, United States
Boston Medical Center

Boston, Massachusetts, 02118, United States
Bozeman Health Deaconess Hospital

Bozeman, Montana, 59715, United States
CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ)

Québec, Quebec, G1R 2J6, Canada
CHUM - Centre Hospitalier de l'Universite de Montreal

Montreal, Quebec, H2X 3E4, Canada
CIUSSSEMTL-Hopital Maisonneuve-Rosemont

Montreal, Quebec, H1T 2M4, Canada
Carle Cancer Center

Urbana, Illinois, 61801, United States
Carolina Regional Cancer Center

Myrtle Beach, South Carolina, 29577, United States
Case Western Reserve University

Cleveland, Ohio, 44106, United States
Cedars Sinai Medical Center

Los Angeles, California, 90048, United States
Central Maryland Radiation Oncology in Howard County

Columbia, Maryland, 21044, United States
Centre De Sante Et De Services Sociaux De Chicoutimi

Chicoutimi, Quebec, G7H 5H6, Canada
Centre Hospitalier Universitaire de Sherbrooke-Fleurimont

Sherbrooke, Quebec, J1H 5N4, Canada
Christiana Care Health System-Christiana Hospital

Newark, Delaware, 19718, United States
Christiana Care Health System-Concord Health Center

Chadds Ford, Pennsylvania, 19317, United States
Cleveland Clinic Akron General

Akron, Ohio, 44307, United States
Cleveland Clinic Cancer Center Independence

Independence, Ohio, 44131, United States
Cleveland Clinic Cancer Center Mansfield

Mansfield, Ohio, 44906, United States
Cleveland Clinic Cancer Center Strongsville

Strongsville, Ohio, 44136, United States
Cleveland Clinic Cancer Center/Fairview Hospital

Cleveland, Ohio, 44111, United States
Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
Cleveland Clinic Wooster Family Health and Surgery Center

Wooster, Ohio, 44691, United States
Cleveland Clinic-Weston

Weston, Florida, 33331, United States
Coborn Cancer Center at Saint Cloud Hospital

Saint Cloud, Minnesota, 56303, United States
Corewell Health Grand Rapids Hospitals - Butterworth Hospital

Grand Rapids, Michigan, 49503, United States
Cotton O'Neil Cancer Center / Stormont Vail Health

Topeka, Kansas, 66606, United States
Crossroads Cancer Center

Effingham, Illinois, 62401, United States
Crozer Regional Cancer Center at Brinton Lake

Glen Mills, Pennsylvania, 19342, United States
Crozer-Keystone Regional Cancer Center at Broomall

Broomall, Pennsylvania, 19008, United States
Dartmouth Cancer Center - North

Saint Johnsbury, Vermont, 05819, United States
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

Lebanon, New Hampshire, 03756, United States
Decatur Memorial Hospital

Decatur, Illinois, 62526, United States
Dickstein Cancer Treatment Center

White Plains, New York, 10601, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
East Jefferson General Hospital

Metairie, Louisiana, 70006, United States
Emory Saint Joseph's Hospital

Atlanta, Georgia, 30342, United States
Emory University Hospital Midtown

Atlanta, Georgia, 30308, United States
Emory University Hospital/Winship Cancer Institute

Atlanta, Georgia, 30322, United States
Farmington Health Center

Farmington, Utah, 84025, United States
Fremont - Rideout Cancer Center

Marysville, California, 95901, United States
Froedtert Menomonee Falls Hospital

Menomonee Falls, Wisconsin, 53051, United States
Froedtert West Bend Hospital/Kraemer Cancer Center

West Bend, Wisconsin, 53095, United States
Geauga Hospital

Chardon, Ohio, 44024, United States
Geisinger Medical Center

Danville, Pennsylvania, 17822, United States
Geisinger Wyoming Valley/Henry Cancer Center

Wilkes-Barre, Pennsylvania, 18711, United States
Gene Upshaw Memorial Tahoe Forest Cancer Center

Truckee, California, 96161, United States
Genesys Hurley Cancer Institute

Flint, Michigan, 48503, United States
Gibbs Cancer Center-Pelham

Greer, South Carolina, 29651, United States
Goshen Center for Cancer Care

Goshen, Indiana, 46526, United States
Grady Health System

Atlanta, Georgia, 30303, United States
Gundersen Lutheran Medical Center

La Crosse, Wisconsin, 54601, United States
Guthrie Medical Group PC-Robert Packer Hospital

Sayre, Pennsylvania, 18840, United States
Heartland Regional Medical Center

Saint Joseph, Missouri, 64506, United States
Helen F Graham Cancer Center

Newark, Delaware, 19713, United States
Henry Ford Cancer Institute-Downriver

Brownstown, Michigan, 48183, United States
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Henry Ford Macomb Hospital-Clinton Township

Clinton Township, Michigan, 48038, United States
Henry Ford West Bloomfield Hospital

West Bloomfield, Michigan, 48322, United States
Hillcrest Hospital Cancer Center

Mayfield Heights, Ohio, 44124, United States
Huntsman Cancer Institute/University of Utah

Salt Lake City, Utah, 84112, United States
Intermountain Medical Center

Murray, Utah, 84107, United States
Iowa Methodist Medical Center

Des Moines, Iowa, 50309, United States
Jefferson Abington Hospital

Abington, Pennsylvania, 19001, United States
Juravinski Cancer Centre at Hamilton Health Sciences

Hamilton, Ontario, L8V 5C2, Canada
Kaiser Permanente Cancer Treatment Center

South San Francisco, California, 94080, United States
Kaiser Permanente Los Angeles Medical Center

Los Angeles, California, 90027, United States
Kaiser Permanente Medical Center - Santa Clara

Santa Clara, California, 95051, United States
Kaiser Permanente Oakland-Broadway

Oakland, California, 94611, United States
Kaiser Permanente-Rancho Cordova Cancer Center

Rancho Cordova, California, 95670, United States
Kansas City Veterans Affairs Medical Center

Kansas City, Missouri, 64128, United States
Kantonsspital Aarau

Aarau, 5001, Switzerland
Karmanos Cancer Institute at McLaren Greater Lansing

Lansing, Michigan, 48910, United States
LDS Hospital

Salt Lake City, Utah, 84143, United States
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

Savannah, Georgia, 31405, United States
Logan Health Medical Center

Kalispell, Montana, 59901, United States
Logan Regional Hospital

Logan, Utah, 84321, United States
London Regional Cancer Program

London, Ontario, N6A 4L6, Canada
Los Angeles General Medical Center

Los Angeles, California, 90033, United States
Lovelace Radiation Oncology

Albuquerque, New Mexico, 87109, United States
Lowell General Hospital

Lowell, Massachusetts, 01854, United States
Loyola University Medical Center

Maywood, Illinois, 60153, United States
MaineHealth Maine Medical Center - Portland

Portland, Maine, 04102, United States
MaineHealth Maine Medical Center- Scarborough

Scarborough, Maine, 04074, United States
Marin Cancer Care Inc

Greenbrae, California, 94904, United States
Marin General Hospital

Greenbrae, California, 94904, United States
Mary Imogene Bassett Hospital

Cooperstown, New York, 13326, United States
Mayo Clinic Health System Eau Claire Hospital-Luther Campus

Eau Claire, Wisconsin, 54703, United States
Mayo Clinic Health System-Franciscan Healthcare

La Crosse, Wisconsin, 54601, United States
Mayo Clinic Health Systems-Mankato

Mankato, Minnesota, 56001, United States
Mayo Clinic in Florida

Jacksonville, Florida, 32224-9980, United States
Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States
McFarland Clinic - Ames

Ames, Iowa, 50010, United States
McKay-Dee Hospital Center

Ogden, Utah, 84403, United States
McLaren Cancer Institute-Central Michigan

Mount Pleasant, Michigan, 48858, United States
McLaren Cancer Institute-Clarkston

Clarkston, Michigan, 48346, United States
McLaren Cancer Institute-Flint

Flint, Michigan, 48532, United States
McLaren Cancer Institute-Lapeer Region

Lapeer, Michigan, 48446, United States
McLaren Cancer Institute-Macomb

Mount Clemens, Michigan, 48043, United States
McLaren Cancer Institute-Northern Michigan

Petoskey, Michigan, 49770, United States
McLaren Cancer Institute-Owosso

Owosso, Michigan, 48867, United States
McLaren-Port Huron

Port Huron, Michigan, 48060, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Memorial Medical Center-Las Cruces

Las Cruces, New Mexico, 88011, United States
Mercy Cancer Center - Cape Girardeau

Cape Girardeau, Missouri, 63703, United States
Mercy Cancer Center-Elyria

Elyria, Ohio, 44035, United States
Mercy Hospital Saint Louis

St Louis, Missouri, 63141, United States
Michigan Healthcare Professionals Clarkston

Clarkston, Michigan, 48346, United States
Michigan Healthcare Professionals Farmington

Farmington Hills, Michigan, 48334, United States
Michigan Healthcare Professionals Troy

Troy, Michigan, 48098, United States
NYP/Weill Cornell Medical Center

New York, New York, 10065, United States
Naval Medical Center - Portsmouth

Portsmouth, Virginia, 23708-2197, United States
New Mexico Oncology Hematology Consultants

Albuquerque, New Mexico, 87109, United States
New York-Presbyterian/Brooklyn Methodist Hospital

Brooklyn, New York, 11215, United States
North Coast Cancer Care

Sandusky, Ohio, 44870, United States
North Kansas City Hospital

Kansas City, Missouri, 64116, United States
Northeast Radiation Oncology Center

Dunmore, Pennsylvania, 18512, United States
Northwell Health Imbert Cancer Center

Bay Shore, New York, 11706, United States
Northwell Health/Center for Advanced Medicine

Lake Success, New York, 11042, United States
Novant Cancer Institute Radiation Oncology - Supply

Supply, North Carolina, 28462, United States
Novant Health Cancer Institute Radiation Oncology - Wilmington

Wilmington, North Carolina, 28401, United States
Novant Health Forsyth Medical Center

Winston-Salem, North Carolina, 27103, United States
Novant Health Presbyterian Medical Center

Charlotte, North Carolina, 28204, United States
OSF Saint Francis Medical Center

Peoria, Illinois, 61637, United States
OSF Saint Francis Radiation Oncology at Peoria Cancer Center

Peoria, Illinois, 61615, United States
Ochsner Medical Center Jefferson

New Orleans, Louisiana, 70121, United States
Ogden Regional Medical Center

Ogden, Utah, 84405, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Overlake Medical Center

Bellevue, Washington, 98004, United States
Owensboro Health Mitchell Memorial Cancer Center

Owensboro, Kentucky, 42303, United States
Penrose-Saint Francis Healthcare

Colorado Springs, Colorado, 80907, United States
Pomona Valley Hospital Medical Center

Pomona, California, 91767, United States
Prisma Health Cancer Institute - Eastside

Greenville, South Carolina, 29615, United States
Prisma Health Cancer Institute - Faris

Greenville, South Carolina, 29605, United States
Prisma Health Cancer Institute - Seneca

Seneca, South Carolina, 29672, United States
Prisma Health Cancer Institute - Spartanburg

Boiling Springs, South Carolina, 29316, United States
ProMedica Flower Hospital

Sylvania, Ohio, 43560, United States
Queen's Medical Center

Honolulu, Hawaii, 96813, United States
Reading Hospital

West Reading, Pennsylvania, 19611, United States
Riverton Hospital

Riverton, Utah, 84065, United States
Rohnert Park Cancer Center

Rohnert Park, California, 94928, United States
Roswell Park Cancer Institute

Buffalo, New York, 14263, United States
SIH Cancer Institute

Carterville, Illinois, 62918, United States
Saint Francis Cancer Center

Greenville, South Carolina, 29607, United States
Saint Luke's Hospital of Duluth

Duluth, Minnesota, 55805, United States
Saskatoon Cancer Centre

Saskatoon, Saskatchewan, S7N 4H4, Canada
Self Regional Healthcare

Greenwood, South Carolina, 29646, United States
Siteman Cancer Center at Saint Peters Hospital

City of Saint Peters, Missouri, 63376, United States
Siteman Cancer Center at West County Hospital

Creve Coeur, Missouri, 63141, United States
Siteman Cancer Center-South County

St Louis, Missouri, 63129, United States
South Jordan Health Center

South Jordan, Utah, 84009, United States
South Sacramento Cancer Center

Sacramento, California, 95823, United States
Spartanburg Medical Center

Spartanburg, South Carolina, 29303, United States
Stanford Cancer Institute Palo Alto

Palo Alto, California, 94304, United States
The Cancer Center of Hawaii-Liliha

Honolulu, Hawaii, 96817, United States
The Cancer Center of Hawaii-Pali Momi

‘Aiea, Hawaii, 96701, United States
The Permanente Medical Group-Roseville Radiation Oncology

Roseville, California, 95678, United States
The Radiation Oncology Center-Hilton Head/Bluffton

Hilton Head Island, South Carolina, 29926, United States
The Research Institute of the McGill University Health Centre (MUHC)

Montreal, Quebec, H3H 2R9, Canada
The University of Kansas Cancer Center - Olathe

Olathe, Kansas, 66061, United States
The University of Kansas Cancer Center-South

Kansas City, Missouri, 64131, United States
Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107, United States
TidalHealth Nanticoke / Allen Cancer Center

Seaford, Delaware, 19973, United States
Trinity Health Grand Rapids Hospital

Grand Rapids, Michigan, 49503, United States
Trinity Health Saint Joseph Mercy Hospital Ann Arbor

Ann Arbor, Michigan, 48106, United States
Trinity Health Saint Joseph Mercy Oakland Hospital

Pontiac, Michigan, 48341, United States
Trinity Health Saint Mary Mercy Livonia Hospital

Livonia, Michigan, 48154, United States
UC Comprehensive Cancer Center at Silver Cross

New Lenox, Illinois, 60451, United States
UCHealth Memorial Hospital Central

Colorado Springs, Colorado, 80909, United States
UCHealth University of Colorado Hospital

Aurora, Colorado, 80045, United States
UH Seidman Cancer Center at Firelands Regional Medical Center

Sandusky, Ohio, 44870, United States
UH Seidman Cancer Center at Lake Health Mentor Campus

Mentor, Ohio, 44060, United States
UH Seidman Cancer Center at Southwest General Hospital

Middleburg Heights, Ohio, 44130, United States
UHHS-Chagrin Highlands Medical Center

Beachwood, Ohio, 44122, United States
UHHS-Westlake Medical Center

Westlake, Ohio, 44145, United States
UM Baltimore Washington Medical Center/Tate Cancer Center

Glen Burnie, Maryland, 21061, United States
UM Sylvester Comprehensive Cancer Center at Coral Gables

Coral Gables, Florida, 33146, United States
UM Sylvester Comprehensive Cancer Center at Deerfield Beach

Deerfield Beach, Florida, 33442, United States
UNC Health Cancer Care Raleigh

Raleigh, North Carolina, 27607, United States
UNC Lineberger Comprehensive Cancer Center

Chapel Hill, North Carolina, 27599, United States
UPMC Pinnacle Cancer Center/Community Osteopathic Campus

Harrisburg, Pennsylvania, 17109, United States
USC / Norris Comprehensive Cancer Center

Los Angeles, California, 90033, United States
UT Southwestern/Simmons Cancer Center-Dallas

Dallas, Texas, 75390, United States
UTMB Cancer Center at Victory Lakes

League City, Texas, 77573, United States
UW Health Carbone Cancer Center Rockford

Rockford, Illinois, 61114, United States
University Hospitals Parma Medical Center

Parma, Ohio, 44129, United States
University of Alabama at Birmingham Cancer Center

Birmingham, Alabama, 35233, United States
University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72205, United States
University of California Davis Comprehensive Cancer Center

Sacramento, California, 95817, United States
University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637, United States
University of Kansas Cancer Center

Kansas City, Kansas, 66160, United States
University of Kansas Cancer Center - Lee's Summit

Lee's Summit, Missouri, 64064, United States
University of Kansas Cancer Center - North

Kansas City, Missouri, 64154, United States
University of Kansas Cancer Center-Overland Park

Overland Park, Kansas, 66210, United States
University of Maryland Radiation Oncology Center at Union Hospital

Elkton, Maryland, 21921, United States
University of Maryland/Greenebaum Cancer Center

Baltimore, Maryland, 21201, United States
University of Miami Miller School of Medicine-Sylvester Cancer Center

Miami, Florida, 33136, United States
University of Michigan Health - Sparrow Lansing

Lansing, Michigan, 48912, United States
University of Michigan Health - West

Wyoming, Michigan, 49519, United States
University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of South Alabama Mitchell Cancer Institute

Mobile, Alabama, 36688, United States
University of Texas Medical Branch

Galveston, Texas, 77555-0565, United States
University of Wisconsin Carbone Cancer Center - University Hospital

Madison, Wisconsin, 53792, United States
Utah Cancer Specialists-Salt Lake City

Salt Lake City, Utah, 84106, United States
Utah Valley Regional Medical Center

Provo, Utah, 84604, United States
Vanderbilt University/Ingram Cancer Center

Nashville, Tennessee, 37232, United States
Vince Lombardi Cancer Clinic - Oshkosh

Oshkosh, Wisconsin, 54904, United States
Vince Lombardi Cancer Clinic-Sheboygan

Sheboygan, Wisconsin, 53081, United States
Vince Lombardi Cancer Clinic-Two Rivers

Two Rivers, Wisconsin, 54241, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
Wayne State University/Karmanos Cancer Institute

Detroit, Michigan, 48201, United States
Weisberg Cancer Treatment Center

Farmington Hills, Michigan, 48334, United States
Wentworth-Douglass Hospital

Dover, New Hampshire, 03820, United States
West Michigan Cancer Center

Kalamazoo, Michigan, 49007, United States
Yale University

New Haven, Connecticut, 06520, United States
Zablocki Veterans Administration Medical Center

Milwaukee, Wisconsin, 53295, United States

Conditions

Explore the condition pages connected to this study.

PROSTATE ADENOCARCINOMA STAGE I PROSTATE ADENOCARCINOMA AJCC V7 STAGE II PROSTATE ADENOCARCINOMA AJCC V7 STAGE III PROSTATE ADENOCARCINOMA AJCC V7