Radiotherapy revolution: could 5 sessions replace 25 for endometrial cancer?
NCT ID NCT07675733
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This trial explores whether a new type of radiotherapy called CT online-adaptive radiotherapy can safely deliver treatment for endometrial cancer in just 5 sessions over a week and a half, instead of the usual 25 sessions over 5 weeks. The study includes 30 adults who have had surgery for endometrial cancer and need post-operative radiotherapy. Researchers will monitor side effects, treatment feasibility, and quality of life for up to 2 years after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Hypofractionated CT online adaptive radiotherapy (CT-OART)
- What this could lead to
- If successful, this could make post-operative radiotherapy for endometrial cancer much shorter and more convenient, reducing treatment from 5 weeks to just 1.5 weeks.
- What could go wrong
- This is a small, early feasibility study with only 30 participants, so results may not apply to all patients. The higher dose per session could increase side effects, and the technology may not work smoothly in all cases.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Royal Marsden Hospital - Sutton
Sutton, SM2 5PT, United Kingdom
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