Radiotherapy revolution: could 5 sessions replace 25 for endometrial cancer?

NCT ID NCT07675733

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This trial explores whether a new type of radiotherapy called CT online-adaptive radiotherapy can safely deliver treatment for endometrial cancer in just 5 sessions over a week and a half, instead of the usual 25 sessions over 5 weeks. The study includes 30 adults who have had surgery for endometrial cancer and need post-operative radiotherapy. Researchers will monitor side effects, treatment feasibility, and quality of life for up to 2 years after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hypofractionated CT online adaptive radiotherapy (CT-OART)

What this could lead to

If successful, this could make post-operative radiotherapy for endometrial cancer much shorter and more convenient, reducing treatment from 5 weeks to just 1.5 weeks.

What could go wrong

This is a small, early feasibility study with only 30 participants, so results may not apply to all patients. The higher dose per session could increase side effects, and the technology may not work smoothly in all cases.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

endometrial carcinoma endometrium neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Royal Marsden Hospital - Sutton

    Sutton, SM2 5PT, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact