New shigella vaccine shows promise in human trial

NCT ID NCT06615375

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 2 times

Summary

This study tests a new vaccine called Shigella4V2 to see if it can protect people from shigellosis, a severe diarrheal disease. About 120 healthy adults will receive either the vaccine or a placebo and then be exposed to the bacteria in a controlled setting. The goal is to see if the vaccine reduces the number of people who get sick.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Hope Clinic of Emory University

    Atlanta, Georgia, 30030, United States

  • Johns Hopkins Center for Immunization Research

    Baltimore, Maryland, 21205, United States

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Other studies related to the condition(s) this trial covers.