New shigella vaccine shows promise in early trial

NCT ID NCT06615375

First seen Feb 14, 2026 · Last updated May 22, 2026 · Updated 13 times

Summary

This study tests a new vaccine called Shigella4V2 to see if it can protect healthy adults from shigellosis, a diarrheal disease caused by Shigella bacteria. About 120 volunteers aged 18-50 will receive either the vaccine or a placebo and then be exposed to the bacteria in a controlled setting. The goal is to see if the vaccine reduces the number of people who get sick.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Hope Clinic of Emory University

    Atlanta, Georgia, 30030, United States

  • Johns Hopkins Center for Immunization Research

    Baltimore, Maryland, 21205, United States

Conditions

Explore the condition pages connected to this study.