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Night-Shift workers: could a gut bug and plant compound boost your metabolism?

NCT ID NCT07440147

Recruiting now Disease control Sponsor: FH Joanneum Gesellschaft mbH Source: ClinicalTrials.gov ↗

First seen Feb 28, 2026 · Last updated May 23, 2026 · Updated 13 times

Summary

This study is testing whether taking a supplement containing a beneficial gut bacterium (Akkermansia muciniphila) and a plant compound (berberine) can improve how the body uses insulin in night-shift workers. Night-shift work often disrupts sleep and eating patterns, raising the risk of obesity and diabetes. The study will involve 200 healthcare and industrial workers in Austria and Denmark, who will take either the supplement or a placebo for 12 weeks, then switch after a break. The main goal is to see if the supplement improves insulin sensitivity, with secondary checks on gut health, inflammation, and sleep quality.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • FH JOANNEUM University of Applied Sciences

    RECRUITING

    Graz, Styria, 8020, Austria

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

CIRCADIAN RHYTHM DISORDERS GUT MICROBIOTA MODULATION OBESITY & OVERWEIGHT PREDIABETES (INSULIN RESISTANCE, IMPAIRED GLUCOSE TOLERANCE) PREDIABETES (INSULIN RESISTANCE, IMPAIRED GLUCOSE TOLERANCE)