Simple gel may prevent painful side effect of liver cancer drug

NCT ID NCT07560566

First seen May 14, 2026 · Last updated May 24, 2026 · Updated 3 times

Summary

This study tests if applying a topical gel (indomethacin) to the hands before starting sorafenib can prevent or reduce hand-foot syndrome, a common and painful side effect. About 39 adults with advanced liver cancer will use the gel twice daily for up to 12 weeks. The goal is to see if this simple approach can help patients stay on their cancer treatment longer with fewer skin problems.

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Contacts and locations

Locations

  • National Taiwan University Hospital

    RECRUITING

    Taipei, 10002, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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