Arm cuff before surgery may shield brain from injury, new trial hopes to prove
NCT ID NCT07420153
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a simple procedure called remote ischemic preconditioning (RIPC) — briefly restricting blood flow to an arm or leg — can reduce brain injury after non-cardiac surgery. The trial will include 216 older adults at risk for postoperative delirium. Researchers will measure a protein in the blood that signals nerve damage, comparing those who receive RIPC the day before surgery to those who receive routine care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
remote ischemic preconditioning (a procedure using brief blood flow restriction to an arm or leg)
What this could lead to
If it works, this could point toward a simple, low-cost way to protect the brain during surgery and reduce confusion or memory problems afterward.
What could go wrong
This is a small, early-stage trial (216 people) testing a biomarker, not clinical outcomes. The procedure may not reduce actual brain injury or delirium, and results may not apply to all surgery patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Locations
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University Medical Center Hamburg-Eppendorf
RECRUITINGHamburg, Free and Hanseatic City of Hamburg, 20246, Germany
Contact Email: •••••@•••••