New drug trial for aggressive blood cancers ends early

NCT ID NCT05961839

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 26 times

Summary

This early-stage study tested a new drug called SGR-2921 in adults with relapsed or refractory acute myeloid leukemia or high-risk myelodysplastic syndrome. The main goal was to find a safe dose and check for side effects. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

  • Colorado Blood Cancer Institute

    Denver, Colorado, 80218, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Oncology Associates of Oregon, P.C.

    Eugene, Oregon, 97401, United States

  • Oregon Health & Science University - Knight Cancer Institute - Center of Hematologic Malignancies

    Portland, Oregon, 97239, United States

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

  • St. David's South Austin Medical Center

    Austin, Texas, 78745, United States

  • The Ohio State University Wexner Medical Center - James Cancer Hospital

    Columbus, Ohio, 43210, United States

  • The University of Kansas Clinical Research Center

    Fairway, Kansas, 66205, United States

  • Thomas Jefferson University, Sidney Kimmel Cancer Center, Clinical Research Organization

    Philadelphia, Pennsylvania, 19107, United States

  • TriStar Bone Marrow Transplant, LLC

    Nashville, Tennessee, 37203, United States

Conditions

Explore the condition pages connected to this study.