Cancer drug trial halted early: limited hope for rare tumors

NCT ID NCT03165721

First seen Feb 18, 2026 · Last updated Apr 25, 2026 · Updated 10 times

Summary

This study tested a drug called SGI-110 (guadecitabine) in people aged 12 and older with rare cancers like wild-type GIST, pheochromocytoma, paraganglioma, or HLRCC-related kidney cancer that had not responded to other treatments. The goal was to see if the drug could shrink tumors or slow their growth. The study was stopped early after enrolling only 9 participants, so the results are limited.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.