Experimental cancer drug tested in rare tumors – study stopped early

NCT ID NCT03165721

First seen Feb 18, 2026 · Last updated Jun 09, 2026 · Updated 20 times

Summary

This study tested a drug called SGI-110 (guadecitabine) in people aged 12 and older with rare cancers like wild-type GIST, pheochromocytoma, paraganglioma, or HLRCC-related kidney cancer that had not responded to other treatments. Participants received daily injections for 5 days every 28 days. The study was stopped early after enrolling only 9 people, and its main goal was to see if the drug could shrink tumors.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.