Blood transfusion breakdown: could donor sex be the key to saving lives?

NCT ID NCT06840756

First seen Feb 11, 2026 · Last updated May 12, 2026 · Updated 14 times

Summary

This study looks at whether giving critically ill ICU patients blood from a donor of the same sex (sex-matched) versus the opposite sex (sex-mismatched) affects their chances of survival. Over 11,000 adults who need a blood transfusion will be randomly assigned to one of the two groups. The main goal is to see if sex-matching lowers the risk of death within 30 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hamilton General Hospital

    RECRUITING

    Hamilton, Ontario, L8L 2X2, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Kingston Health Sciences Centre

    NOT_YET_RECRUITING

    Kingston, Ontario, K7L 2V7, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Lakeridge Health Oshawa

    NOT_YET_RECRUITING

    Oshawa, Ontario, L1G 8A2, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • London Health Sciences Centre

    NOT_YET_RECRUITING

    London, Ontario, N6A 5W9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mount Sinai Hospital

    NOT_YET_RECRUITING

    Toronto, Ontario, M5G 1X5, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Sunnybrook Health Sciences Centre

    NOT_YET_RECRUITING

    Toronto, Ontario, M4N 3M5, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Ottawa Hospital

    NOT_YET_RECRUITING

    Ottawa, Ontario, K1Y 1J8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Toronto General Hospital

    NOT_YET_RECRUITING

    Toronto, Ontario, M5G 2C4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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