New anesthesia combo may calm kids after surgery
NCT ID NCT06624592
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving sevoflurane plus dexmedetomidine reduces emergence delirium (confusion and agitation) in children aged 2-7 after surgery, compared to isoflurane alone. About 400 children having ear, eye, or urology procedures will take part. The main goal is to see how many children have delirium and how long they stay in recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- sevoflurane and dexmedetomidine (drug combination) vs isoflurane (drug)
- What this could lead to
- If this works, it could point to a better anesthesia method that reduces confusion and distress in young children after surgery.
- What could go wrong
- This is a single-center trial with 400 children, so results may not apply to all hospitals or surgeries. The drugs are already in use, so the main risk is that the combination may not reduce delirium as hoped.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mayo Clinic in Rochester
RECRUITINGRochester, Minnesota, 55905, United States
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