Blood filter device tested to fight COVID-19 organ failure
NCT ID NCT04547257
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This trial tests a device called Seraph 100, a blood filter used to treat severe COVID-19. The goal is to see if filtering the blood can reduce organ failure in patients with COVID-19 who are in the intensive care unit. The study enrolled 42 adults with confirmed COVID-19 and organ problems. Researchers measure changes in organ function over 48 hours and track survival.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Seraph 100 blood filter
What this could lead to
If it works, this could provide a new way to treat severe COVID-19 by filtering harmful substances from the blood, potentially reducing organ failure and improving survival.
What could go wrong
This is a small early study with only 42 participants, so results may not apply to everyone. The device is experimental and may not improve outcomes or could cause complications from the filtering process.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hospital Clinico San Carlos
Madrid, 28040, Spain
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Hospital Universitari Vall d'Hebron
Barcelona, 08035, Spain
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Klinikum Aschaffenburg-Alzenau
Aschaffenburg, 63739, Germany
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Universitätsklinikum Essen
Essen, 45147, Germany
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Vivantes Klinikum Neukölln
Berlin, 12351, Germany