Diet and drug combo aim to tame tumor side effects
NCT ID NCT05300048
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new drug called serabelisib combined with a diet that lowers insulin levels, with or without another chemotherapy drug, in people with advanced solid tumors that have a specific genetic change (PIK3CA mutation). The goal was to see if the diet could reduce side effects and improve how well the drug works. The study was stopped early, and only 34 people were enrolled.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Avera Cancer Institute
Sioux Falls, South Dakota, 57105, United States
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Baptist Hospitals of Southeast Texas
Beaumont, Texas, 77701, United States
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Community Health Network, Inc.
Indianapolis, Indiana, 46250, United States
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East Carolina University
Greenville, North Carolina, 27858, United States
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Englewood Health
Englewood, New Jersey, 07631, United States
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Hoag Memorial Hospital Presbyterian
Newport Beach, California, 92663, United States
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Lumi Research
Kingwood, Texas, 77339, United States
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Mayo Clinic - Rochester
Rochester, Minnesota, 55902, United States
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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New Jersey Cancer Care, PA
Belleville, New Jersey, 07109, United States
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Northwell Health
Lake Success, New York, 11042, United States
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Oncology Consultants, PA
Houston, Texas, 77030, United States
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Pacific Cancer Specialists
Anaheim, California, 92801, United States
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University of Alabama
Birmingham, Alabama, 35429, United States
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University of Pennsylvania Health System, Perelman Center for Advanced Medicine
Philadelphia, Pennsylvania, 19104, United States
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Valkyrie Clinical Trials
Los Angeles, California, 90067, United States