New strategy: removing tumors one by one after chemo for stomach and pancreatic cancers
NCT ID NCT07282912
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tests whether a series of procedures to remove cancerous tumors, given one after another, can improve outcomes for people with stage IV foregut cancers (like stomach, pancreas, or bile duct cancer) who have no detectable cancer DNA in their blood after initial chemotherapy. About 54 participants will be randomly assigned to either standard care or standard care plus these sequential tumor-removal procedures. The main goal is to see if this approach delays cancer progression or death.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Sequential cytoreductive intervention (a series of procedures to remove cancerous tumors one after another)
What this could lead to
If successful, this approach could extend the time patients with advanced foregut cancer live without their disease getting worse, potentially pointing to a new treatment strategy.
What could go wrong
This is a small, early-phase trial with only 54 participants, so results may not apply to everyone. The procedures carry risks like infection or complications, and the benefit over standard care is not yet proven.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Smilow Cancer Center
RECRUITINGNew Haven, Connecticut, 06519, United States