Blood test could help doctors choose the right drug for deadly sepsis

This small, completed pilot study tested whether two substances in the blood (renin and DPP3) can predict which patients with severe septic shock will respond better to a drug called angiotensin II versus standard vasopressor therapy. The goal was to gather information to design a larger future trial, not to prove one treatment is better than the other. Researchers compared the two treatments in 40 adult patients whose blood pressure remained dangerously low despite initial medication.