Tracking infection markers over time may spot sepsis sooner in cancer patients
NCT ID NCT07795502
First seen Aug 31, 2026 · Last updated Sep 02, 2026 · Updated 2 times
Summary
This study tests whether tracking changes in infection markers and blood culture results over time can help detect sepsis earlier and monitor treatment in adults with cancer. Researchers will follow 100 patients with suspected sepsis during their hospital stay and for up to 30 days. They will collect data on blood cultures, inflammatory markers, and clinical severity to see if these changes relate to treatment response, complications, and survival. The goal is to improve early detection and management of sepsis in this high-risk group.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to earlier sepsis detection and better monitoring in cancer patients, potentially reducing severe complications and deaths.
- What could go wrong
- This is an observational study, so it cannot prove cause and effect. The findings may not apply to all cancer patients or settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Jul 2026
- Expected to finish
-
Aug 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will consist of adult patients with solid or hematological malignancies who present with suspected sepsis and have at least one blood culture obtained as part of routine clinical care. Participants will be followed during hospitalization and for up to 30 days after enrollment to evaluate dynamic infection kinetics and clinical outcomes.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Confirmed diagnosis of a solid or hematological malignancy. * Clinical suspicion of sepsis according to treating physicians. * At least one blood culture obtained before or shortly after initiation of antimicrobial therapy. * Availability for clinical follow-up during hospitalization. Exclusion Criteria: * Patients receive palliative care only. * Absence of blood culture sampling. * Incomplete clinical or laboratory data. * Refusal to participate in the study, when applicable.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Cancer are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Sohag Oncology Center
RECRUITINGSohag, Sohag Governorate, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Évaluation de la détresse post-traumatique relative au cancer dans l'année suivant le diagnostic chez les patients et les aidants et identification de leurs attentes envers un accompagnement personnalisé
- Development and pilot implementation of a novel remote patient monitoring program for cancer patients initiating cancer-directed therapy: the SHIELD (Smart health integration for early life-saving detection)
- The promoting resilience in stress Management-Social needs (PRISM-SN) intervention for adolescents and young adults with cancer: a randomized controlled trial
- Persistent inflammation, immunosuppression and catabolism syndrome (PICS): a new horizon for surgical critical care subtitle: cardiac dysfunction in older sepsis survivors subtitle: development of a designer Proline-Rich antimicrobial peptide chaperone protein inhibitor (DPC) for treating sepsis
- An equity focused intervention to improve utilization of guideline concordant extended venous thromboembolism prophylaxis after major cancer surgery
- A randomized clinical trial of early empiric Anti-Mycobacterium tuberculosis therapy for sepsis in Sub-Saharan africa