Could skipping axillary surgery be safe for early breast cancer patients?

NCT ID NCT05315154

First seen May 08, 2026 · Last updated May 08, 2026

Summary

This study looks at whether women with early breast cancer (tumors smaller than 5 cm) and no signs of cancer in the lymph nodes can safely skip sentinel lymph node biopsy. About 800 women will be randomly assigned to either have the biopsy or no axillary surgery at all. The goal is to see if avoiding surgery affects cancer recurrence or survival.

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Contacts and locations

Locations

  • Hospital Barão de Lucena

    Recife, Pernambuco, Brazil

  • Hospital Celso Pierro - PUCC

    Campinas, São Paulo, Brazil

  • Hospital Federal da Lagoa

    Rio de Janeiro, Rio de Janeiro, Brazil

  • Hospital Geral de Fortaleza

    Fortaleza, Ceará, Brazil

  • Hospital da Mulher

    São Paulo, São Paulo, Brazil

  • Hospital da Mulher Prof.Dr. J A Pinotti - UNICAMP

    Campinas, São Paulo, Brazil

  • Hospital de Amor - Fundação Pio XII

    Barretos, São Paulo, Brazil

  • Hospital de Clínica da Universidade Federal de Minas Gerais

    Belo Horizonte, Minas Gerais, Brazil

  • Hospital de Clínicas de Porto Alegre - UFRS

    Porto Alegre, Rio Grande do Sul, Brazil

  • Hospital do Câncer de Muriaé da Fundação Cristiano Varella

    Muriaé, Minas Gerais, Brazil

  • Hospital do Servidor Público Estadual

    São Paulo, São Paulo, Brazil

  • Liga Norte Riograndense Contra o Câncer

    Natal, Rio Grande do Norte, Brazil

  • Maternidade Dona Iris

    Goiânia, Goiás, Brazil

  • Oncocenter

    Teresina, Piauí, Brazil

  • Unesp

    Botucatu, São Paulo, Brazil

  • Universidade Federal de Goiás

    Goiânia, Goiás, Brazil

  • Universidade Federal do Paraná

    Curitiba, Paraná, Brazil

  • Universidade Federal do Piauí

    Teresina, Piauí, Brazil

Conditions

Explore the condition pages connected to this study.