Could a simple pill stop lungs from scarring? new trial launches
NCT ID NCT06714123
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether the drug senicapoc can prevent lung scarring from getting worse in people with progressive fibrotic interstitial lung disease (ILD) or idiopathic pulmonary fibrosis (IPF). About 140 adults will take either senicapoc or a placebo daily for 26 weeks, and doctors will track lung function, side effects, and quality of life. The goal is to see if senicapoc can slow the decline in breathing capacity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Senicapoc (a drug taken as tablets)
- What this could lead to
- If it works, this could point toward a new treatment to slow lung scarring and preserve breathing function in people with fibrotic lung disease.
- What could go wrong
- This is an early Phase 2 trial with only 140 participants, so results may not confirm benefit. The drug may cause side effects or fail to outperform placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Aarhus University Hospital
RECRUITINGAarhus N, 8200, Denmark
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Division of Respiratory Sciences, Glenfield Hospital
NOT_YET_RECRUITINGLeicester, LE3 9QP, United Kingdom
-
Kardiologisk Forskningsenhed 2161, Rigshospitalet
RECRUITINGCopenhagen, 2100, Denmark
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Tartu University Hospital,
RECRUITINGTartu, 50406, Estonia
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University of East Anglia
NOT_YET_RECRUITINGNorwich, NR4 7TJ, United Kingdom
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new pill slow lung scarring in IPF?
- Beyond the lungs: the hidden emotional toll of IPF medications
- Can umbilical cord stem cells ease a scarring lung disease?
- Spotting hidden blood clots in scarred lungs: a study hunts for clues
- What makes someone stop a lung fibrosis drug? a study asks patients directly
- A smarter way to track lung disease? new platform aims to personalize COPD and IPF care