Could a simple pill stop lungs from scarring? new trial launches

NCT ID NCT06714123

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether the drug senicapoc can prevent lung scarring from getting worse in people with progressive fibrotic interstitial lung disease (ILD) or idiopathic pulmonary fibrosis (IPF). About 140 adults will take either senicapoc or a placebo daily for 26 weeks, and doctors will track lung function, side effects, and quality of life. The goal is to see if senicapoc can slow the decline in breathing capacity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Senicapoc (a drug taken as tablets)
What this could lead to
If it works, this could point toward a new treatment to slow lung scarring and preserve breathing function in people with fibrotic lung disease.
What could go wrong
This is an early Phase 2 trial with only 140 participants, so results may not confirm benefit. The drug may cause side effects or fail to outperform placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aarhus University Hospital

    RECRUITING

    Aarhus N, 8200, Denmark

  • Division of Respiratory Sciences, Glenfield Hospital

    NOT_YET_RECRUITING

    Leicester, LE3 9QP, United Kingdom

  • Kardiologisk Forskningsenhed 2161, Rigshospitalet

    RECRUITING

    Copenhagen, 2100, Denmark

  • Tartu University Hospital,

    RECRUITING

    Tartu, 50406, Estonia

  • University of East Anglia

    NOT_YET_RECRUITING

    Norwich, NR4 7TJ, United Kingdom

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