New hope for shrinking painful tumors in adults with rare genetic disorder
NCT ID NCT04924608
Summary
This global study is testing whether the drug selumetinib can shrink painful, inoperable tumors in adults with Neurofibromatosis Type 1 (NF1). About 145 participants will be randomly assigned to receive either selumetinib or a placebo to see which is better at reducing tumor size and relieving chronic pain. The main goal is to see if the drug leads to a confirmed partial or complete shrinkage of the target tumor by the end of the treatment period.
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Contacts and locations
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Locations
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Research Site
Gainesville, Florida, 32610, United States
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Rockville, Maryland, 20852, United States
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St Louis, Missouri, 63156, United States
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Commack, New York, 11725, United States
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Melbourne, 3000, Australia
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St Leonards, 2065, Australia
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Porto Alegre, 90035-903, Brazil
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Ribeirão Preto, 14051-140, Brazil
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São Paulo, 045202-001, Brazil
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Toronto, Ontario, M5G 2C4, Canada
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Montreal, Quebec, H4A 3J1, Canada
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Beijing, 100070, China
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Beijing, 100730, China
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Guangzhou, 510060, China
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Shenyang, 110001, China
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Créteil, 94000, France
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Lyon, 69008, France
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Toulouse, 31059, France
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Hamburg, 20246, Germany
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Tübingen, 72076, Germany
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Würzburg, 97080, Germany
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Milan, 20133, Italy
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Naples, 80131, Italy
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Roma, 00165, Italy
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Minatoku, 105-8471, Japan
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Nagoya, 466-8560, Japan
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Shinjuku-ku, 160-8582, Japan
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Bydgoszcz, 85-094, Poland
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Moscow, 115522, Russia
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Moscow, 125412, Russia
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Badalona, 08916, Spain
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Madrid, 28041, Spain
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London, SE1 9RT, United Kingdom
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Manchester, M20 4BX, United Kingdom
Conditions
Explore the condition pages connected to this study.