New drug combo shows promise for Tough-to-Treat biliary cancers

NCT ID NCT02151084

First seen Dec 29, 2025 · Last updated May 16, 2026 · Updated 19 times

Summary

This study tests whether adding the targeted drug selumetinib to standard chemotherapy (cisplatin and gemcitabine) helps shrink tumors better than chemo alone in people with advanced bile duct or gallbladder cancer. About 57 adults who have not had prior treatment for their cancer will receive either the drug combo or chemo alone. The goal is to see if the new combination slows cancer growth and improves survival.

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Contacts and locations

Locations

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2M9, Canada

Conditions

Explore the condition pages connected to this study.