New hope for patients with advanced multiple myeloma: drug combo shows promise
NCT ID NCT04414475
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a drug called selinexor combined with a low-dose steroid (dexamethasone) in people with multiple myeloma that has stopped responding to many other treatments. Some participants will also receive another drug, bortezomib. The goal is to see if these combinations can shrink tumors and control the disease. About 127 adults aged 18 and older with specific types of refractory myeloma will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Assuta Ashdod Medical Center
RECRUITINGAshdod, Ashdod, 7747629, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Barzilai Medical Center
RECRUITINGAshkelon, 7830604, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Bnai-Zion Medical Center
RECRUITINGHaifa, Haifa District, 3108, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Emek Medical Center
RECRUITINGAfula, Afula, 1834111, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
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General Hospital of Athens "Alexandra"
RECRUITINGAttiki, Athens, 11528, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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General Hospital of Athens "Evangelismos"
RECRUITINGAthens, Attica, 10676, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hadassah Medical Center
RECRUITINGJerusalem, Jerusalem, 9112001, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Meir Medical Center
COMPLETEDKfar Saba, 4428164, Israel
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Rabin Medical Center (Beilinson Hospital)
RECRUITINGPetah Tikva, Petah Tikva, 49100, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Rambam Health Care Campus
RECRUITINGHaifa, Haifa District, 3109601, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shaare Zedek Medical Center
RECRUITINGJerusalem, Jerusalem, 9103102, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Soroka University Medical Center
ACTIVE_NOT_RECRUITINGBeersheba, Israel
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Tel Aviv Sourasky Medical Center
RECRUITINGTel Aviv, Tel Aviv, 64239, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Chaim Sheba Medical Center at Tel HaShomer
RECRUITINGRamat Gan, Ramat Gan, 52621, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Theageneion Cancer Hospital
RECRUITINGThessaloniki, Thessaloniki, 54007, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University General Hospital of Patras
COMPLETEDPátrai, Achaia, 2654, Greece