New drug combo tested for Tough-to-Treat brain cancer

NCT ID NCT05698147

Summary

This study is testing a new three-drug combination for adults with central nervous system lymphoma that has returned or not responded to prior treatment. The goal is to find a safe and effective dose of the oral drug selinexor when added to standard chemotherapy drugs (methotrexate and rituximab). Researchers will enroll about 30 patients to first determine the best dose and then see how well the combination controls the cancer.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tiantan Hospital, Capital Medical University

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Hematology, Huashan Hospital, Fudan University

    RECRUITING

    Shanghai, Shanghai Municipality, 200040, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oncology Department of The First Affiliated Hospital of Zhengzhou University

    NOT_YET_RECRUITING

    Zhengzhou, Henan, 450052, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The First Affiliated Hospital Of Anhui Medical University

    NOT_YET_RECRUITING

    Hefei, Anhui, China

    Contact

  • The First Affiliated Hospital Of Fujian Medical University

    NOT_YET_RECRUITING

    Fuzhou, Fujian, China

    Contact

Conditions

Explore the condition pages connected to this study.