Scientists test sedatives to unlock Smoking's brain secrets

NCT ID NCT05505630

Summary

This small, early-stage study aimed to understand how different sedative medications affect cigarette cravings and smoking behavior. Researchers gave 20 daily smokers intravenous infusions of ketamine, midazolam, dexmedetomidine, or a placebo saline solution. They measured changes in cravings, withdrawal symptoms, and actual smoking behavior before and after each infusion to learn how these drugs interact with smoking-related brain pathways.

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Contacts and locations

Locations

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27157, United States

Conditions

Explore the condition pages connected to this study.