Which sedative is safer for emergency intubation? large trial seeks answers

NCT ID NCT05277896

First seen Sep 30, 2025 · Last updated May 14, 2026 · Updated 29 times

Summary

This study looked at over 2,300 critically ill adults who needed an emergency breathing tube. It compared two common sedatives, ketamine and etomidate, to see which one leads to fewer deaths and heart problems. The goal was to find the safer option for this high-risk procedure.

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Contacts and locations

Locations

  • Denver Health Medical Center

    Denver, Colorado, 80204, United States

  • Hennepin County Medical Center

    Minneapolis, Minnesota, 55415, United States

  • UAB Hospital

    Birmingham, Alabama, 35233, United States

  • University of Colorado Denver

    Aurora, Colorado, 80045, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Wake Forest Baptist Medical Center

    Winston-Salem, North Carolina, 27157, United States

Conditions

Explore the condition pages connected to this study.