New sedation drug may reduce breathing risks during heart procedure
NCT ID NCT07532733
First seen Apr 28, 2026
Summary
This study compares two sedation approaches during a minimally invasive heart valve replacement (TAVI) in 80 elderly patients. One group receives dexmedetomidine, a sedative that may cause less breathing depression, while the other gets standard propofol-remifentanil. Researchers will monitor breathing problems like low oxygen or slow breathing during the procedure.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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HUB Erasme
RECRUITINGBrussels, 1070, Belgium
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dexmedetomidine
What this could lead to
If dexmedetomidine proves safer, it could become the preferred sedation method for TAVI, reducing breathing complications in elderly patients.
What could go wrong
This is a small, early-phase study (80 participants) comparing two sedation drugs. Results may not apply to all patients or settings, and both drugs have known side effects like low heart rate or blood pressure.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.