New IV drug shows promise for inflammatory conditions in early trial

NCT ID NCT06130540

First seen Jan 29, 2026 · Last updated Apr 28, 2026 · Updated 13 times

Summary

This early-stage study tested an intravenous (IV) form of secukinumab in 65 adults with giant cell arteritis (GCA) or polymyalgia rheumatica (PMR), two inflammatory conditions. The goal was to see how the drug moves through the body and whether it is safe. Participants received multiple IV infusions, and researchers monitored side effects and drug levels in the blood.

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Contacts and locations

Locations

  • Accurate Clinical Research Inc

    San Antonio, Texas, 78229, United States

  • Altoona Center for Clin Res

    Duncansville, Pennsylvania, 16635, United States

  • FL Medical Clinic Orlando Health

    Zephyrhills, Florida, 33542, United States

  • Novartis Investigative Site

    Uherské Hradiště, Uherske Hradiste, 686 01, Czechia

  • Novartis Investigative Site

    Brno-Bohunice, 625 00, Czechia

  • Novartis Investigative Site

    Florence, FI, 50134, Italy

  • Novartis Investigative Site

    Reggio Emilia, RE, 42123, Italy

  • Novartis Investigative Site

    Lisbon, 1649 035, Portugal

  • Novartis Investigative Site

    Santiago de Compostela, Galicia, 15706, Spain

  • Novartis Investigative Site

    Madrid, 28009, Spain

  • Novartis Investigative Site

    Madrid, 28046, Spain

  • Novartis Investigative Site

    Basel, 4031, Switzerland

  • Novartis Investigative Site

    Bern, 3010, Switzerland

  • Novartis Investigative Site

    Sankt Gallen, 9007, Switzerland

  • Overlake Internal Med Associates

    Bellevue, Washington, 98004, United States

  • Rheumatology Associates of South Florida

    Boca Raton, Florida, 33486, United States

  • Rheumatology Pulmonary Clinic

    Beckley, West Virginia, 25801, United States

  • West Tennessee Research Institute

    Jackson, Tennessee, 38305, United States

  • Willow Rheumatology Wellness

    Willowbrook, Illinois, 60527, United States

Conditions

Explore the condition pages connected to this study.